Boronic acid-linked fluorescent and colorimetric probes for copper ions.

نویسندگان

  • K M K Swamy
  • Sung-Kyun Ko
  • Soo Kyung Kwon
  • Ha Na Lee
  • Chun Mao
  • Joung-Min Kim
  • Keun-Hyeung Lee
  • Jinheung Kim
  • Injae Shin
  • Juyoung Yoon
چکیده

The first examples of boronic acid-linked fluorescent and colorimetric chemosensors for copper ions are reported; the monoboronic acid-conjugated rhodamine probe displays a highly selective fluorescent enhancement with Cu2+ among the various metal ions whereas the fluorescence of the bisboronic acid-conjugated fluorescein probe is selectively quenched by Cu2+, probably by way of a PET mechanism.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ditopic boronic acid and imine-based naphthalimide fluorescence sensor for copper(II).

Copper ions are essential for many biological processes. However, high concentrations of copper can be detrimental to the cell or organism. A novel naphthalimide derivative bearing a monoboronic acid group (BNP) was investigated as a Cu(2+) selective fluorescent sensor in living cells. This derivative is one of the rare examples of reversible fluorescent chemosensors for Cu(2+) which uses a bor...

متن کامل

Excitation and emission wavelength ratiometric cyanide-sensitive probes for physiological sensing.

We characterize three new fluorescent probes that show both spectral shifts and intensity changes in the presence of aqueous cyanide, allowing for both excitation and fluorescence emission wavelength ratiometric and colorimetric sensing. The relatively high binding constants of the probes for cyanide enables a distinct colorimetric change to be visually observed with as little as 10 microM cyan...

متن کامل

Wavelength-ratiometric near-physiological pH sensors based on 6-aminoquinolinium boronic acid probes.

We describe the pH response of a set of isomeric water-soluble fluorescent probes based on both the 6-aminoquinolinium and boronic acid moieties. These probes show spectral shifts and intensity changes with pH, in a wavelength-ratiometric and colorimetric manner. Subsequently, changes in pH can readily be determined around the physiological level. Although boronic acid containing probes are kno...

متن کامل

Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.

A fluorescent sensor prochelator, FlamB (fluorescein hydrizido 2-imidophenylboronic ester), has been developed that selectively probes for copper under conditions of oxidative stress. High levels of hydrogen peroxide trigger the release of a boronic ester masking group from the prochelator to unveil a metal chelator, FlamS (fluorescein hydrizido 2-imidophenol), that provides a modest fluorescen...

متن کامل

A wavelength–ratiometric fluoride-sensitive probe based on the quinolinium nucleus and boronic acid moiety

We report a new water-soluble fluorescent probe sensitive to aqueous fluoride. The probe shows spectral shifts and intensity changes in the presence of fluoride, in a wavelength ratiometric and colorimetric manner, enabling the detection of fluoride concentrations at visible wavelengths, in the concentration range ≈1–300 mM. The probes response is based on the ability of the boronic acid group ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 45  شماره 

صفحات  -

تاریخ انتشار 2008